Ketone bodies, or ketones, serve as an alternative energy source for your brain cells and cells in other tissues when glucose isn’t readily available. Some of this fat is used by the liver to produce ketone bodies. In this state, your body starts to break down and burn fat. When you are fast for ~12 hours or more, you enter a metabolic state called ketosis. Researchers are now trying to unlock what can hack this autophagy process for increased longevity. Recent research suggests that chronic disruption of the autophagy processes can be linked to numerous negative health outcomes. Fasting-induced autophagy has also been shown to dramatically increase the amount autophagosomes (organelles that carry out recycling of cellular components during autophagy) in the liver, heart, muscle and even brain tissue during the fasted state. The autophagy process has been linked to protective benefits against neurodegenerative diseases in the brain like Parkinson’s, Alzheimer’s and dementia. Autophagy – the cellular recycling mechanismĪutophagy is our cells’ self-digestive mechanism that recycles waste material and old proteins as energy. Autophagosomes within a cell, recycling cellular components included misfolded proteins. You may be familiar with the various stages of fasting, but let’s review the key points to guide you in understanding how coffee consumption can affect your fast and promote the cellular recycling process of autophagy. Protection against Type 2 diabetes ( 3)ĭrinking too much coffee can result in very unpleasant adverse effects, especially related to the caffeine (6) that is found in the coffee.Protection against Parkinson’s disease ( 1, 2).Protection against various form of cancer including breast, liver, colon, endometrial and prostate cancer.Meta-analyses of observational and randomized controlled trials suggest many potential health benefits and some risks, but overall a reduced risk of mortality associated with coffee consumption.Ĭoffee consumption has been associated with the following health outcomes: Benefits and Risks of Coffee ConsumptionĪ comprehensive review published in the Annual Review of Nutrition focused on coffee and caffeine consumption with various health outcomes. Begin your autophagy journey with coffee and fasting. For now, the focus will be on the primary health effects that decades of scientific research have shown us on this popular beverage, and how it can be a powerful tool when combined with intermittent fasting. I will be covering the differences in brewing techniques, coffee additives and popular meal replacement forms of coffee like the popular “bulletproof” coffee in another blog post. With hundreds of different types of brews, roasts and blends of coffee alone, without considering the variety of different creamers, butters, oils, spices and sweeteners that can complement your preferred cup of coffee, it’s easy to see how any casual consumer or coffee-aficionado could create a beverage unique to their liking. Click here to pre-register for our Coffee AMA and be notified when it starts!)Ĭoffee is one of the most widely consumed beverages worldwide. Learn more: This Is Your Fasted Body on Coffee (plus Ask Me Anything during a Coffee AMA at LIFEApps this week! I will be responding to your questions LIVE on Facebook Messenger from 10AM – 1PM Central US time on Weds, May 22nd. Decades of research suggests that potential health benefits of coffee consumption include protection against type 2 diabetes, Parkinson’s disease, cardiovascular disease, liver disease, liver cancer and improved heart health. Coffee consumption may have effects on Autophagy, a process of cellular component recycling that also occurs during intermittent fasting. But if you have ever thought about giving up coffee, you might want to think again. If you are anything like me, your day probably doesn’t get started until you have had your morning cup of coffee.
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